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The ACT Network




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The Accrual to Clinical Trials Network, or ACT, is a Clinical and Translational Science Awards (CTSA) program-wide federated network that aims to significantly increase participant accrual into clinical trials. ACT currently has 48 CTSA sites connected to the network and consists of data derived from the electronic medical records of over 125 million patients. ACT helps clinical investigators with discovering cohorts before the start of a trial, establishing feasibility of a clinical protocol for grant applications, and with identifying patients from multiple sites. The data exposed to the network consists of demographics, diagnoses, procedures, laboratory results and medications. These data are available through a user interface for defining inclusion and exclusion criteria and exploring patient cohorts and potential sites for collaboration. The University of Utah is a participating CTSA site on the ACT network.

The National Patient-Centered Clinical Research Network (PCORnet), an initiative of the Patient-Centered Outcomes Research Institute (“PCORI”), comprises a community of patients and their families, researchers, scientists, clinicians, health systems, and other committed individuals and organizations dedicated to the common purpose of accelerating patient- centered outcomes research. Through this partnership, and within an environment of mutual trust and shared responsibility, PCORnet is transforming the culture of clinical research from one directed by researchers to one driven by the needs of patients and those who care for them. [PCORnet Quick Guide]

The National COVID Cohort Collaborative (N3C) is a clinical repository that is being established to address critical research questions related to the COVID‑19 pandemic. The goals of N3C are to enable rapid collection of clinical data at the peak of the pandemic in order to contribute towards understanding of the disease, inform design of clinical studies and trials, and identification of effective interventions. N3C aggregates clinical data derived from electronic medical records of patients who were tested for COVID-19 (positive and negative results) at CTSA program institutions and partners. Limited datasets consisting of demographics, diagnoses, procedures, laboratory results, and medications harmonized to the OMOP model are stored in the repository and will be available within the National Institutes of Health’s analytics environments. The University of Utah is participating in this national endeavor and is contributing its data. [N3C Brief Overview]

TriNetX is a global health research network connecting clinical data of over one hundred million patients to industry’s top healthcare organizations, biopharmaceutical companies and contract research organizations (CROs). TriNetX shares real-world data to make clinical and observational research easier and more efficient. It combines real time access to longitudinal clinical and genomic data which optimizes protocol design and feasibility, site selection, and patient recruitment. [TriNetX Brief Overview]

Other Research Resources

Biomedical Informatics Core (BMIC) has a catalog of local and national resources available to the Investigators at the University of Utah. Follow this link to access the resources: [Research Data Resource Catalog]

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Core Administration

Julio Facelli, PhD
BMIC Director

Ram Gouripeddi, MBBS, MS
BMIC Assistant Director