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What Is the Internal Advisory Committee

What Is the Internal Advisory Committee?

What is the Internal Advisory Committee (IAC)?

The Internal Advisory Committee has the responsibility for the review, approval, and oversight of all research projects requesting CCTS support. The chairman of the committee is J. Robinson Singleton, MD. The committee meets monthly to evaluate proposals based upon scientific merit and need for center resources. Approved research projects are prioritized using these two factors. The committee is responsible for the designation of the category of inpatient days and outpatient visits for each research project proposed to the center as category A, B, or D, including the classification of research sponsored by industry.

What is the IAC process?

The Clinical Services Center (CSC) Director assigns a primary reviewer to each protocol submitted. The reviewer critiques the study verbally and in a written report on the qualifications of the principal investigator, proposed science, suitability of study design, strengths and weaknesses, and need for center resources.

If the Committee approves the protocol with no changes, the investigator can begin to use CCTS resources immediately (assuming IRB approval has been granted). If the study is not approved as submitted, the protocol will be returned to the investigator with specific suggestions for revision. Consideration following resubmission is usually expedited.

After each meeting, the principal investigator of each study reviewed is sent a written notice indicating the action taken by the committee at the meeting.

No studies requiring center support can take place without Internal Advisory Committee approval, except when temporary approval is given by the chairman for urgent studies created by an unexpected opportunity to study unusual patients.

A protocol can be reviewed simultaneously by the IRB and the Internal Advisory Committee, but the study cannot be activated on the GCRC until a copy of the IRB letter of approval is received at the CCTS office.

View the IAC Committee

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